A protein family as ChEMBL classifies it.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 198 |
| Activity range, pActivity | -0.18 to 7.7 |
| Median activity | 5.85 |
| Endpoint | Measurements |
|---|---|
| IC50 | 121 |
| Ki | 77 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 83 |
| Three | 0 |
| Four or more | 3 |
| Family | Shared compounds |
|---|---|
| Oxidoreductase | 85 |
| Protease | 2 |
| Family A G protein-coupled receptor | 1 |
| Primary active transporter | 1 |
| Cytochrome P450 | 1 |
| Eraser | 1 |