A protein family as ChEMBL classifies it.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 237 |
| Activity range, pActivity | 3.0 to 8.62 |
| Median activity | 5.64 |
| Endpoint | Measurements |
|---|---|
| IC50 | 214 |
| Ki | 23 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 191 |
| Three | 2 |
| Four or more | 5 |
| Family | Shared compounds |
|---|---|
| Transferase | 101 |
| Kinase | 91 |
| Protease | 6 |
| Oxidoreductase | 5 |
| Cytochrome P450 | 4 |
| Hydrolase | 3 |