A protein family as ChEMBL classifies it.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 371 |
| Activity range, pActivity | 2.64 to 8.0 |
| Median activity | 4.62 |
| Endpoint | Measurements |
|---|---|
| IC50 | 359 |
| Ki | 9 |
| EC50 | 3 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 19 |
| Three | 45 |
| Four or more | 14 |
| Family | Shared compounds |
|---|---|
| Oxidoreductase | 73 |
| Eraser | 56 |
| Reader|Writer | 9 |
| Kinase | 3 |
| Electrochemical transporter | 3 |
| Phosphatase | 3 |