A protein family as ChEMBL classifies it.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 243 |
| Activity range, pActivity | 2.68 to 8.59 |
| Median activity | 5.14 |
| Endpoint | Measurements |
|---|---|
| IC50 | 229 |
| Kd | 9 |
| Ki | 5 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 26 |
| Three | 20 |
| Four or more | 18 |
| Family | Shared compounds |
|---|---|
| Eraser | 19 |
| Oxidoreductase | 18 |
| Writer | 14 |
| Kinase | 12 |
| Family A G protein-coupled receptor | 10 |
| Eraser|Reader | 9 |