A protein family as ChEMBL classifies it.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 85 |
| Activity range, pActivity | 4.04 to 7.38 |
| Median activity | 5.58 |
| Endpoint | Measurements |
|---|---|
| IC50 | 70 |
| Ki | 12 |
| Kd | 3 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 6 |
| Three | 2 |
| Four or more | 7 |
| Family | Shared compounds |
|---|---|
| Nuclear receptor | 8 |
| Cytochrome P450 | 6 |
| Oxidoreductase | 6 |
| Family A G protein-coupled receptor | 4 |
| Eraser | 4 |
| Electrochemical transporter | 3 |