A protein family as ChEMBL classifies it.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 334 |
| Activity range, pActivity | 2.6 to 11.0 |
| Median activity | 6.87 |
| Endpoint | Measurements |
|---|---|
| IC50 | 208 |
| Ki | 64 |
| EC50 | 62 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 111 |
| Three | 11 |
| Four or more | 13 |
| Family | Shared compounds |
|---|---|
| Cytochrome P450 | 61 |
| Voltage-gated ion channel | 52 |
| Family A G protein-coupled receptor | 21 |
| Electrochemical transporter | 16 |
| Ligand-gated ion channel | 11 |
| Oxidoreductase | 10 |