Enzymes that join two molecules using energy from a triphosphate.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 332 |
| Activity range, pActivity | 3.92 to 10.3 |
| Median activity | 8.1 |
| Endpoint | Measurements |
|---|---|
| Kd | 145 |
| IC50 | 105 |
| Ki | 73 |
| EC50 | 9 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 71 |
| Three | 9 |
| Four or more | 13 |
| Family | Shared compounds |
|---|---|
| Electrochemical transporter | 31 |
| Transferase | 24 |
| Cytochrome P450 | 20 |
| Oxidoreductase | 18 |
| Kinase | 13 |
| Voltage-gated ion channel | 10 |