A protein family as ChEMBL classifies it.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 154 |
| Activity range, pActivity | 3.73 to 10.0 |
| Median activity | 5.62 |
| Endpoint | Measurements |
|---|---|
| IC50 | 154 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 23 |
| Three | 5 |
| Four or more | 5 |
| Family | Shared compounds |
|---|---|
| Cytochrome P450 | 11 |
| Voltage-gated ion channel | 10 |
| Oxidoreductase | 9 |
| Family A G protein-coupled receptor | 4 |
| Transferase | 4 |
| Electrochemical transporter | 3 |