Enzymes that hydrolyse cyclic nucleotides.
servable in this model
measured here and in at least one other family
involving this family
| Quantity | Value |
|---|---|
| Measurements | 1,558 |
| Activity range, pActivity | 1.74 to 10.85 |
| Median activity | 6.0 |
| Endpoint | Measurements |
|---|---|
| IC50 | 1,427 |
| Ki | 68 |
| Kd | 55 |
| EC50 | 8 |
Every ligand counted here is measured in this family and in at least one other. The question worth asking is how many families a compound reaches altogether, because a compound seen in four families is a very different starting point from one seen in two.
| Families a compound reaches | Compounds |
|---|---|
| Two | 378 |
| Three | 41 |
| Four or more | 40 |
| Family | Shared compounds |
|---|---|
| Family A G protein-coupled receptor | 108 |
| Eraser | 92 |
| Kinase | 89 |
| Voltage-gated ion channel | 80 |
| Cytochrome P450 | 78 |
| Hydrolase | 39 |